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2023
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Spranger Lab demonstrates lymph node microenvironmentsuppresses anti-tumor T cells in the lungFebruary 2, 2023 | ImmunityRead coverage by MIT News |
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Yaffe lab creates atlas of protein kinasesJanuary 11, 2023 | NatureRead coverage by MIT News |
2022
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The Spranger lab joins CPCM! |
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Work from the Vander Heiden lab provides a mechanistic explanation for why hypoxic cancer cells depend on imported lipids for growthJune 23, 2022 | Nature MetabolismRead coverage by Columbia University Irving Medical Center, BioSpace |
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Congratulations to CPCM members Mike Yaffe and Michael Hemann on winning a 2022 Bose grant for ambitious ideas!June 17, 2022Read coverage by MIT News |
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CPCM-member Forest White collaborated with KI colleague Tyler Jacks on deciphering the immunopeptidome in vivo to reveal new tumor antigensJune 15, 2022 |
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Manalis Lab study finds that cells take out the trash before they divideMay 10, 2022 | eLifeRead coverage by MIT News |
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White Lab postdoc and Convergence Scholar Tigist Tamir creates "Edges and Nodes," a video series aimed at demystifying the life of a scientistMarch 2022 |
2021
2020
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Koehler Lab identifies a molecule that could target advanced prostate cancer as well as a variety of other cancersNovember 19, 2020 | Cell Chemical BiologyRead coverage by MIT News |
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Hemann Lab establishes that two treatment methods enhance chemotherapy by the same means: cellular senescence (Study 1; Study 2)November 17, 2020 | PNASRead coverage by MIT Biology News |
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Michael Hemann presents "New Mechanisms for Old Cancer Drugs" as part of the Dana-Farber/Harvard Cancer seminar seriesOctober 1, 2020 |
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The Hemann lab's inTRINSIC model investigates subtype-specific susceptibilities in glioblastomaSeptember 16, 2020 | Molecular Systems Biology |
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The Yaffe Lab presents Transite, a computational approach to identifying RNA-binding proteinsAugust 25, 2020 | Cell ReportsRead coverage by KI News |
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The Yaffe Lab and colleagues describe the concept of augmented synthetic lethality which can enhance chemotherapy responseAugust 17, 2020 | Nature CommunicationsRead coverage by KI News |
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Yaffe Lab research shows that BRD4 prevents the accumulation of R-loops and protects against transcription-replication collision events and DNA damageAugust 14, 2020 | Nature CommunicationsRead coverage by KI News, Author's view |
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Allison Lau and colleagues in the Vander Heiden Lab dissect cell type-specific metabolism in pancreatic ductal adenocarcinomaJuly 10, 2020 | eLifeRead coverage by Science in Boston |
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Angela Koehler's Kronos Bio reports positive results in preclinical study of investigational CDK9 inhibitorJuly 9, 2020 |
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Manalis lab monitors cell growth efficiency by studying cell size and cell cycleJune 24, 2020 | PNAS |
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Lauren Stopfer and colleagues from the White and Lauffenburger labs are counting antigensJune 2, 2020 | Nature Communications |
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Congratulations to Lauren Stopfer (White lab) and Suzy Ramos (Hemann lab) on receiving a 2020 Margaret A. Cunningham Immune Mechanisms in Cancer Research Fellowship AwardApril 2020
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CPCM research, industry, and patients: Coming full circleMarch 23, 2020Read coverage by MIT News |
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Hemann lab’s Sarna Jeewajee brings along music while studying cancerFebruary 2, 2020
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2019
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Matt Vander Heiden in the Spotlight: Understanding cancer metabolismDecember 4, 2019
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Congratulations to Rob Wilson (Koehler lab) on receiving the 2019 Peter Karches Mentorship Prize!November 15, 2019
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Vander Heiden and Jacks labs join forces to identify a new therapeutic target for small cell lung cancerNovember 6, 2019 | Science Translational MedicineRead coverage by MIT News and on the NIH Director's blog |
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Congratulations to Lauren Stopfer (White lab) on her 2020 Siebel Scholar Award for academic achievement and leadership!September 25, 2019Read coverage by MIT News |
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Yaffe lab identifies a new drug combination to kill cancer cellsJuly 10, 2019 | Cell SystemsRead coverage by MIT News |
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Hemann lab and collaborators discovered a compound that makes cancer cells more susceptible to chemotherapyJune 6, 2019 | Cell |
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New study from the Vander Heiden lab on the role of serine availability in tumor growthJune 4, 2019 | Cell Metabolism |
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Congratulations to CPCM member Angela Koehler for receiving the NSF Career Award!May 1, 2019 |
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Vander Heiden lab and colleagues develop a new method to measure tumor nutrient availability in miceApril 16, 2019 | ElifeRead more: MIT News, KI News and The Atlantic |
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Koehler lab reports a novel small molecule that attenuates Myc-driven transcriptionMarch 14, 2019 | Cell Chemical Biology |
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Angela Koehler receives the MIT Junior Bose Award for Teaching ExcellenceMarch 2019 |
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New Yaffe lab study on ROS and oxidative stress in cancer cellsFebruary 20, 2019 | Cell Systems |
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The Manalis lab joins CPCM! |
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An insightful essay by CPCM Director Michael Yaffe in Science SignalingJanuary 22, 2019 | Science SignalingRead coverage by KI News |
2018
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Learn more about the Koehler lab array-based ligand discovery platform2018 | Methods in Enzymology |
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Congratulations to Shanarya Sivanand (Vander Heiden lab) on receiving a postdoctoral fellowship from the Damon Runyon Cancer Research Foundation! |
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White lab paper just accepted: "A proteomics approach to profiling the temporal translational response to stress and growth"November 1, 2018 | iScience |
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New study from the Vander Heiden lab on isocitrate dehydrogenase and 2-hydroxyglutarate productionOctober 30, 2018 | Journal of Biological Chemistry |
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Congratulations to Shelby Doyle (Koehler lab graduate student) on receiving the 2018 Peter Karches Mentorship Prize!October 29, 2018 |
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The Vander Heiden lab explores the role of PKM2 in pancreatic cancerOctober 23, 2018 | Cancer & Metabolism |
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CPCM faculty member Angela Koehler reflects on Kendal Square's riseOctober 18, 2018 | MIT Spectrum |
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Discovery of synergistic combination therapy heads to a clinical trialOctober 3, 2018 |
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Meet the 2019 class of Convergence ScholarsNovember 7, 2018 Read coverage by KI News |
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Congratulations to Allison Lau (Vander Heiden lab postdoc) on receiving the Koch Institute Stanley (1958) and Bonnie Klein Research Travel Fellowship!
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New publication from the Yaffe lab in Cell SystemsSeptember 19, 2018 | Cell Systems Read more about this work: Cell Systems Preview, KI news. |
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Congratulations to Azucena (Susy) Ramos (Hemann lab MD/PhD student) for receiving the prestigious Ruth L. Kirschstein Award (F31) from the NIH!
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Great article about CPCM member Matt Vander HeidenAugust 28, 2018 | MIT News |
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Congratulations to Tatiana Netterfield (Yaffe lab grad student) on being awarded the NSF Graduate Research Fellowship!
Read more about the 2018 NSF GRFP awardees here. |
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Another informative review from the Vander Heiden lab on cancer cell metabolismAugust 7, 2018 | Disease Models & Mechanisms |
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New study from the Vander Heiden lab on the role of aspartate in cancerJune 25, 2018 | Nature Cell Biology Read coverage by MIT News and Nature News & Views. |
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Vander Heiden lab and clinical collaborators identify a mechanism for tissue wasting in pancreatic cancerJune 20, 2018 | Nature Read more about this work: MIT News, Nature News & Views, STAT News |
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Great perspective from the Vander Heiden lab on how the nutrient environment affects cancer therapyJune 1, 2018 | Science |
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Yaffe/ Floyd/ Hammond lab collaboration: using targeted nanoparticles to fight brain tumorsMay 18, 2018 | Nature Communications Read coverage by MIT News and Nature Nanotechnology News & Views |
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Nick Struntz (Koehler lab postdoc) awarded MIT-GSK Gertrude B. Elion FellowshipApril 17, 2018 | MIT News |
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New study from the Yaffe Lab offers novel insight into colon cancer developmentApril 16, 2018 | PNAS |
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The Man Who Uncovered a New (Old) Way to Fight CancerFebruary 21, 2018 | MIT Technology Review |
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Fine-tuning cancer medicineFebruary 1, 2018 | MIT News |